Crohn’s disease involves the full thickness of the bowel wall. Crohn’s disease can be complicated by fistulas and abscesses.
The most common symptoms of Crohn’s disease are abdominal pain, often in the lower right area, and severe and persistent diarrhea. Rectal bleeding, weight loss, fatigue and fever may also occur. Bleeding may be serious and persistent bleeding to anemia.
Children with Crohn’s disease may suffer delayed development and stunted growth.
Although the true cause of Crohn’s disease still remains unclear, various factors are assumed to play an underlying role in the development of this disease. Among these genetic, immunologic, microbial and dietary factors may have implications.
Environmental factors seem to play an important role in the manifestation, course and prognosis of Crohn’s disease. Epidemiological studies suggest that the prevalence of Crohn’s disease is higher in industrialized countries.
Crohn's disease
