Wednesday, January 20, 2021

Histamine Intolerance: Causes and symptoms

Histamine intolerance is a disease caused by decreased DAO (diamineoxidase) activity leading to elevated plasma histamine levels. Histamine intolerance triggered by fish, cheese, red wine etc. in diamineoxidase-deficient individuals

The diamine oxidase is a sensitive molecule that can be inhibited in its activity by chemical influences. The foods and additives on the right are or contain DAO inhibitors that can block the breakdown of histamine by the DAO.

The clinical signs of histamine intolerance include headaches, rhinopathia, bronchial asthma, tachycardia and arrhythmias, chronic gastritis, small bowel disease, diarrhea and hypotension.

About 1 percent of the population has a histamine intolerance, and four out of five of them are middle-aged. Histamine intolerance is underdiagnosed, mostly because the symptoms are so similar to an allergic reaction that a physician might suspect allergies first and foremost.
Histamine Intolerance: Causes and symptoms

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