Hashimoto’s thyroiditis
Hashimoto’s thyroiditis is named after the doctor who discovered it, Hakaru Hashimoto. It was first described in 1912, can manifest as hyperthyroidism, hypothyroidism, euthyroid goiter or diffuse goiter. With Hashimoto’s the cause of the furnace slowing is attributed to malfunction of the body’s immune system.
Hashimoto’s thyroiditis is a thyroid specific auto-immune disorder in which both humoral and T-cell mediated cellular immune mechanisms play a role.
The body’s natural defenders, antibodies start attacking the thyroid because they misidentify body tissue for that of a foreign invader.
In Hashimoto’s the target of the antibodies is the thyroid gland. It is slowly developing, persistent inflammation of the thyroid resulting in decreased function of the gland.
Although this condition may occur at any age, it is most common among middle-aged women.
Histological, Hashimoto’s thyroiditis demonstrates cellular hyperplasia disruption of follicular cells and infiltration of the gland by lymphocytes, monocytes and plasma cells.
Hashimoto’s thyroiditis
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