In the mild form of aplastic anemia, the blood cells are less drastically reduced in number. Sometimes, a deficiency of some type of blood cell precedes the full-blown development of aplastic anemia.
In severe cases a patient may suffer from heavy or prolonged bleeding, frequently or severe infections and severe anemia.
The major causes for acquired aplastic anemia include exposure to radiation, drugs and other chemicals, viruses, immune diseases and other disease processes.
Genetic syndromes associated with aplastic anemia include Fanconi’s anemia, Familiar aplastic anemia, Schwachman-Diamond syndrome and other nonhematologic syndromes.